Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells
نویسندگان
چکیده
منابع مشابه
Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells.
For symmetrically dividing cells, large variations in the cell cycle time are typical, even among clonal cells. The consequence of this variation is important in stem cell differentiation, tissue and organ size control, and cancer development, where cell division rates ultimately determine the cell population. We explore the connection between cell cycle time variation and population-level fluc...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2013
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2013.0325